##With the siSPOTR tools you can:

• Identify candidate siRNA/shRNA sequences for your gene of interest with a low potential for off-targeting.
• Evaluate the off-targeting potential for any RNAi sequence.
• View a list of all predicted off-targets for siRNA candidates, along with information on the site-type composition and probability of being off-targeted.
• BLAST your sequence to search for siRNA-like on/off-targeting

##Components siSPOTR Project is made of two major components

• base - Database Access layer
• webapp - JAVA Spring/Hibernate Application

# git clone git@github.com:ui-icts/sispotr-project.git
# cd sispotr-project/
# mvn install

1. copy "webapp/src/main/resources/config/safeseed.properties.example" to webapp/src/main/resources/config/safeseed.properties
2. Update with your properties, provide the correct Database URL, username, and password

# cd sispotr-project
# mvn package
# java -jar  webapp/target/dependency/jetty-runner.jar --path /sispotr --port 9090 webapp/target/*.war
# in a browser goto: http://localhost:9090/sispotr
# Default username: admin
# Default password: safeseed

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